TARGET TB is using whole genome sequencing of TB isolates from three contrasting districts of Nepal (Kathmandu, Pyuthan and Banke) to understand how TB transmits within our communities and inform the development of more effective interventions for elimination. A better understanding of current TB transmission patterns in these different settings (urban and rural), and the relative contribution of cross border migration, reactivation of latent TB, drug resistance and strain virulence, will inform effective approaches to targeting resources for TB control in these areas, and serve as a model more broadly, in a rapidly urbanizing Asia. The project is being conducted by a consortium including BNMT, GENETUP, TB Nepal and the University of Melbourne (Australia) in collaboration with the National TB Control Centre (NTCC).
People with TB, TB researchers and scientists, national policy makers